Cardiac and skeletal muscle function depends upon the correct formation of
Cardiac and skeletal muscle function depends upon the correct formation of myofibrils, that are tandem arrays of highly structured actomyosin contractile models called sarcomeres. RNA disturbance silencing, we discover that this formins mDia2, DAAM1, 1009119-65-6 supplier FMNL1, and FMNL2 are needed nonredundantly for myofibrillogenesis. Knockdown phenotypes consist of global lack of myofibril business and faulty … [Read more…]