The p53 gene is rarely mutated in neuroblastoma but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and clinical outcome. amplification. By Cox regression analysis the p53 Pro/Pro genotype seems to be an independent marker of poor prognosis (hazard proportion = 2.74; 95% self-confidence period = 1.14-6.55 = .014) as well … [Read more…]
Oxidative apoptosis and stress are implicated in the pathogenesis of diabetic embryopathy. activation of JNK1/2 signaling caspases 3 and 8 and apoptosis in Sox1+ neural progenitors of the developing neural tube. Our results show that JNK1 and JNK2 are equally involved in diabetic embryopathy and that the oxidative stress-JNK1/2-caspase pathway mediates the proapoptotic signals and … [Read more…]
Objectives: The purpose of this research was to look for the degree of transformation (DC) of 3 resin based endodontic sealers using the DSC technique. through the values of temperature created during each polymerization. The info had been statistically analysed using a Kruskal-Wallis one-way ANOVA multiple range and Student-Newman-Keuls (SNK) exams at a P worth … [Read more…]