GATA6 is a zinc finger transcription element expressed in the colorectal

GATA6 is a zinc finger transcription element expressed in the colorectal epithelium. is certainly amplified in ~10% of esophageal adenocarcinomas and Barrett metaplasia [16]. The transition from normal esophageal epithelium to Barrett metaplasia to adenocarcinoma is usually associated with up-regulation of GATA6 [17]. Further the gene is usually amplified in pancreatiobiliary cancers [12 18 Colorectal … [Read more…]