Tumor immunotherapy and targeted therapy, though less toxic than conventional chemotherapy, can increase the risk of thyroid dysfunction

Tumor immunotherapy and targeted therapy, though less toxic than conventional chemotherapy, can increase the risk of thyroid dysfunction. combined with 131-iodine, administered as a radiotherapeutic agent for tumours derived from neural crest cells, can cause primary hypothyroidism. Bexarotene can produce transient central hypothyroidism by altering the feedback effect of thyroid hormone on the pituitary gland. … [Read more…]

Neurodegenerative diseases are seen as a neuronal degeneration as well as neuroinflammation

Neurodegenerative diseases are seen as a neuronal degeneration as well as neuroinflammation. conditions in which neurons in the central or peripheral nervous system degenerate. Depending on the localization and the neuronal populace that degenerates, different pathologies arise, leading to debilitating symptoms and ultimately patient death. While the process by which neurons undergo degeneration remains elusive, … [Read more…]