Protein kinase A (PKA) activity is pivotal for proper functioning of the human heart, and its dysregulation has been implicated in a variety of cardiac pathologies

Protein kinase A (PKA) activity is pivotal for proper functioning of the human heart, and its dysregulation has been implicated in a variety of cardiac pathologies. of in mice increased cardiac PKA activity, and reduced heart weight and cardiomyocyte size without altering contractile function at 3?months of age. Silencing of provoked PKA\dependent inactivating phosphorylation of … [Read more…]