Supplementary Materialsdjz024_Supplementary_Data. to 6, whereas the cumulative occurrence of toxicity reached 51.7% (95% PI = 40.5% to 66.3%) after six cycles. Toxicity rates ranging from 20.0% to 30.0% in the first cycle were associated with 46.8% (95% PI = 39.5% to 54.2%) and 65.8% (95% PI = 57.7% to 73.1%) cumulative incidence after six cycles. … [Read more…]
Supplementary MaterialsSupplemental Digital Content mao-40-728-s001. 1?mol/L upsurge in TBIL) and total and comparative hearing increases ([95% CI]: 1.4 [0.2, 2.7]?dB and 1.6 [0.2, 3.1]?dB, respectively) in the severe to profound hearing reduction subpopulation. Conclusions: Higher TBIL amounts, within the standard or raised runs mildly, were separately and significantly connected with better hearing result in BSSHL … [Read more…]
Supplementary MaterialsESM 1: (PDF 15. ring. N-Methylation in the diketopiperazine band or prenylation from the tryptophan-containing cyclodipeptides affects the enzyme item and activity range. Tips the DKP bands tend to be catalyzed by cyclodipeptide oxidases (CDOs). This is observed for sp first. KO-2388 (Kanzaki et al. 1999) and 2?years later in (Gondry et al. 2001). … [Read more…]