Simple calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and
Simple calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have already been associated with serious osteoarthritis and many degenerative arthropathies. JNK MAPK pathways, most likely beneath the control of activator proteins-1. NO, a significant mediator of cartilage degradation, could be directly made by BCP crystals in chondrocytes. As well as synovial activation, … [Read more…]