CpG oligodeoxynucleotides (ODNs) upregulate the interleukin-21 receptor (IL21R) and enhance IL-21-mediated
CpG oligodeoxynucleotides (ODNs) upregulate the interleukin-21 receptor (IL21R) and enhance IL-21-mediated cytotoxicity in chronic lymphocytic leukemia (CLL) C cells. NF-B inhibitor, we slow down the CpG ODN-mediated induction of IL21R, showing that CpG-685 upregulates IL21R through an NF-B mediated path hence. These results recommend an choice system for induction of IL-21 receptor in CLL C … [Read more…]