Targeting CAFs CAFs comprise a nice-looking anti-tumor therapeutic focus on
Targeting CAFs CAFs comprise a nice-looking anti-tumor therapeutic focus on. stroma to synthesize, remodel and stiffen the interstitial stroma, which resists the expansion from the DCIS lesion mechanically. The neoplastic epithelium in DCIS lesions responds to these makes by raising their actomyosin stress that drives the set up of focal adhesions to potentiate development factor-dependent … [Read more…]