Genetic disorders from the Ras/MAPK pathway, termed RASopathies, produce several abnormalities,
Genetic disorders from the Ras/MAPK pathway, termed RASopathies, produce several abnormalities, including cutaneous keratodermas. description for the noticed epidermal problems. These findings recommend a mechanism where DSG1 and Erbin cooperate to repress MAPK signaling and promote keratinocyte differentiation. Intro As a hurdle, skin protects microorganisms from environmental pathogens 150915-40-5 IC50 and dehydration, a function that … [Read more…]