The transcription factor C/EBP plays an integral role in monocytic differentiation
The transcription factor C/EBP plays an integral role in monocytic differentiation and inflammation. amounts. Our research elucidates brand-new signalling pathways inducing LAP*/LAP appearance and indicates brand-new alternative PKR features in monocytes. The change from mTOR- to RSK-mediated signalling to orchestrate eIF4B-dependent LAP*/LAP translation, followed by elevated proteins stability but just small mRNA adjustments, could be … [Read more…]