Mutations in ribosomal proteins (RP) genes can lead to the increased
Mutations in ribosomal proteins (RP) genes can lead to the increased loss of erythrocyte progenitor cells and trigger severe anemia. this suppression leads to proteasomal degradation of p53. By re-activating the AKT pathway or by inhibiting GSK-3, a downstream modifier that normally represses AKT signaling, we’re able 608141-41-9 supplier to restore the stabilization of p53. … [Read more…]