A fresh near-infrared fluorescent compound containing two cyclic RGD motifs cypate-[c(RGDfK)]2
A fresh near-infrared fluorescent compound containing two cyclic RGD motifs cypate-[c(RGDfK)]2 (1) was synthesized based on a carbocyanine fluorophore bearing two carboxylic acid groups (cypate) for integrin αvβ3-targeting. novel approaches for exploiting integrin αvβ3 targeting are still needed to improve cancer imaging diagnosis and therapy. As one of the most versatile imaging modalities optical imaging … [Read more…]