Lipoteichoic acid solution (LTA) is important in the pathogenesis of serious
Lipoteichoic acid solution (LTA) is important in the pathogenesis of serious inflammatory responses induced by Gram-positive infection. the inhibitors of cPLA2 (AACOCF3) and COX-2 (NS-398) or transfection with cPLA2 siRNA or COX-2 siRNA, respectively. LTA-stimulated NF-B translocation or cPLA2 phosphorylation was attenuated by pretreatment with “type”:”entrez-nucleotide”,”attrs”:”text message”:”LY294002″,”term_id”:”1257998346″,”term_text message”:”LY294002″LY294002, SB202190, U0126, or SP600125. Furthermore, LTA could … [Read more…]