CDDP [cisplatin or cis-diamminedichloroplatinum(II)] and CDDP-based combination chemotherapy have already been
CDDP [cisplatin or cis-diamminedichloroplatinum(II)] and CDDP-based combination chemotherapy have already been verified effective against gastric cancers. considerably suppress MEK/ERK and PI3K/Akt signalling in CDDP-resistant cells. Furthermore, inhibition of PI3K/Akt pathway without MEK/ERK pathway could inhibit PAK4 activity in these cells. The outcomes were equivalent with those of check at a significance level worth of 0.05 … [Read more…]