The Musashi category of RNA-binding proteins, Musashi1 and Musashi2, regulate self-renewal
The Musashi category of RNA-binding proteins, Musashi1 and Musashi2, regulate self-renewal and differentiation of neuronal and hematopoietic stem cells by modulating protein translation. Msi1 is fixed to neuronal stem cells and regulates their self-renewal, Msi2 is normally predominantly portrayed in hematopoietic stem cells (HSC) and regulates regular hematopoiesis.36, 37 Two main goals of Msi identified … [Read more…]