To examine the part of nuclear element (NF)-B in T cell
To examine the part of nuclear element (NF)-B in T cell advancement and activation in vivo, we produced transgenic mice that express a superinhibitory mutant type of inhibitor B- (IB-A32/36) beneath the control of the T cellCspecific Compact disc2 promoter and enhancer (mutant [m]IB- mice). the mIB- mice had been resistant to -Compact disc3Cmediated apoptosis … [Read more…]