The Gag proteins of HIV-1 are central players in virus particle
The Gag proteins of HIV-1 are central players in virus particle assembly, release, and maturation, and in addition function in the establishment of the productive infection. that little substances that dock in the PI(4,5)P2-binding groove might boost GagCmembrane association by triggering the myristyl change. Such dysregulation of membrane binding activity could disrupt correct Gag concentrating … [Read more…]