Insulin homeostasis in pancreatic -cell is now recognized as a critical
Insulin homeostasis in pancreatic -cell is now recognized as a critical element in the progression of obesity and type II diabetes (T2D). diabetes (T2D) (Ashcroft and Rorsman, 2012), it is crucial CX-4945 to understand the protein interactions that govern the biogenesis and release of insulin into plasma. Orci and colleagues initially described the trafficking itinerary … [Read more…]