Glutamate-activated -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid solution receptors (AMPA-Rs) mediate nearly all excitatory neurotransmission
Glutamate-activated -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid solution receptors (AMPA-Rs) mediate nearly all excitatory neurotransmission in brain and therefore are main drug targets for diseases connected with hyperexcitability or neurotoxicity. network hyperexcitability. Intro Glutamate-activated -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acidity receptors (AMPA-Rs) mediate nearly all mind fast excitatory neurotransmission. The four AMPA-R subunits, GluA1-4, typically assemble as tetrameric cation stations from heterodimers of … [Read more…]