Tuberous sclerosis complicated (TSC) is normally a multisystem hereditary disease that
Tuberous sclerosis complicated (TSC) is normally a multisystem hereditary disease that manifests with mental retardation, tumor formation, autism, and epilepsy. activity in the TSC2+/? CA3 area from the hippocampus. Inhibition of mGluR5 or Erk signaling restores suitable mTOR-dependence to LTD, and considerably decreases epileptiform bursting in TSC2+/? hippocampal pieces. We also survey that adult TSC2+/? … [Read more…]