Background Cellular stress responses trigger signaling cascades that inhibit proliferation and
Background Cellular stress responses trigger signaling cascades that inhibit proliferation and protein translation to help alleviate the stress or if the stress cannot be overcome induce apoptosis. (SCC9, SCC25) cell lines, metformin enhanced gefitinib cytotoxicity only in LKB1 conveying cell lines while both groups showed synergistic cytotoxic effects with lovastatin treatments. Furthermore, the combination of … [Read more…]