Oleanolic acid-derived synthetic triterpenoids are broad spectrum antiproliferative and antitumorigenic agents.
Oleanolic acid-derived synthetic triterpenoids are broad spectrum antiproliferative and antitumorigenic agents. V-FITC binding and cleavage of PARP-1 and procaspases-3,-8 and -9) and reversed the loss of mitochondrial membrane potential and launch of cytochrome c from mitochondria by CDDO-Me. CDDO-Me down-regulated p-Akt, p-mTOR and NF-B (p65) but improved the service of Erk1/2 and NAC clogged the … [Read more…]