Arrays of octameric peptide libraries on cellulose paper were screened through
Arrays of octameric peptide libraries on cellulose paper were screened through the use of 32P-autophosphorylated cGMP-dependent proteins kinase I (cGPK) to recognize peptide sequences with high binding affinity for cGPK. the cGPK substrate series TQAKRKKSLAMFLR, where the serine signifies the phosphate-acceptor site (12, 13). Substitution of the serine by alanine yielded cGPK inhibitors with (Fig. … [Read more…]