Insufficiency or mutation in the p53 tumor suppressor gene commonly occurs
Insufficiency or mutation in the p53 tumor suppressor gene commonly occurs in human being cancer and may donate to disease development and chemotherapy level of resistance. phosphorylation of Bcl-2 are fundamental determinants in 5-FU-induced autophagy. Inhibition of Oligomycin A JNK from the substance SP600125 or Oligomycin A JNK siRNA suppressed autophagy and phosphorylation of c-Jun … [Read more…]