Mutation or epigenetic silencing of the transcription element C/EBP is observed
Mutation or epigenetic silencing of the transcription element C/EBP is observed in ~10% of individuals with extreme myeloid leukemia (AML). reveal critical downstream focuses on for therapeutic treatment potentially. Transcription element CEBPA can be differentially converted into two isoforms of 42 kDa and 30 kDa (Lin et al., 1993). Two thirds of AML instances with … [Read more…]