MHC-peptide tetramers have become essential tools for T-cell analysis, but few
MHC-peptide tetramers have become essential tools for T-cell analysis, but few MHC class II tetramers incorporating peptides from human tumor and self-antigens have been developed. self-antigens, which is usually generally lower than that of peptides from pathogens. NY-ESO-1 (ESO), a tumor-specific antigen of the malignancy/testis group frequently expressed in tumors of different histological types (6), … [Read more…]