NK cell cytotoxicity requires the forming of an actin-rich immunological synapse
NK cell cytotoxicity requires the forming of an actin-rich immunological synapse (IS) having a target cell and the polarization of perforin-containing lytic granules toward the IS. of ATP KU-55933 under conditions of circulation. In NK cells from individuals having a truncation mutation in myosin IIA NK cell cytotoxicity lytic granule penetration into F-actin in the … [Read more…]