OBJECTIVE Bone marrow-derived human mesenchymal stem cells (hMSCs) are capable of
OBJECTIVE Bone marrow-derived human mesenchymal stem cells (hMSCs) are capable of localizing to gliomas after systemic delivery and can be used in glioma therapy. via autocrine and paracrine mechanisms (9). Importantly, hMSCs are known to express the PDGF receptors (PDGFR) on their cell surface (16), and thus their function may be regulated by tumor-derived PDGF-BB. … [Read more…]