In type 1 diabetes, the insulin-producing -cells are destroyed by the
In type 1 diabetes, the insulin-producing -cells are destroyed by the immune system. of TGF-Ctreated bone marrowCderived DCs to activate both CD4+ and CD8+ T cells was reduced. Adding TGF-Cconditioned tolerogenic DCs to the grafted islets led to long-term survival of the graft, demonstrating that TGF-Cinduced tolerogenic DCs can provide an effective means to restore … [Read more…]