The p53 gene is rarely mutated in neuroblastoma but codon 72
The p53 gene is rarely mutated in neuroblastoma but codon 72 polymorphism that modulates its proapoptotic activity might influence cancer risk and clinical outcome. amplification. By Cox regression analysis the p53 Pro/Pro genotype seems to be an independent marker of poor prognosis (hazard proportion = 2.74; 95% self-confidence period = 1.14-6.55 = .014) as well … [Read more…]