The immune system develops in waves during ontogeny, being initially populated
The immune system develops in waves during ontogeny, being initially populated by cells generated from fetal hematopoietic stem cells (HSCs) and later by cells derived from adult HSCs. pro-B cells. In the mouse genome, there are twelve let-7 paralogs that result in the expression of nine distinguishable mature miRNA isoforms (isomiRs) (Fig. S1). The let-7 … [Read more…]