T follicular helper cells (Tfh cells) localize to follicles where they
T follicular helper cells (Tfh cells) localize to follicles where they offer development and selection indicators to mutated germinal middle (GC) B cells therefore promoting their differentiation into high affinity long-lived plasma cells and memory space B cells. Bcl-6+ T cells show up in the T-B boundary immediately after T cell priming and before GC … [Read more…]