Self-renewal and differentiation of mammalian haematopoietic stem cells (HSCs) are controlled
Self-renewal and differentiation of mammalian haematopoietic stem cells (HSCs) are controlled by a specialized microenvironment called the niche’. cortical zone (CZ), from a pool of multipotent progenitors called prohaemocytes present in the medullary zone (MZ)1. In addition, a group of signalling cells, termed posterior signalling centre (PSC), is clustered at the posterior end of the … [Read more…]