Metadherin (mementos an oncogenic program and chemoresistance. and/or caspase-8 down-regulation. Our
Metadherin (mementos an oncogenic program and chemoresistance. and/or caspase-8 down-regulation. Our results suggest that inhibition may be used to restore TRAIL sensitivity in TRAIL-resistant breast cancers. EXPERIMENTAL PROCEDURES Production of Recombinant Human TRAIL (rhTRAIL) rhTRAIL was produced essentially as described previously (23 24 Briefly M15 pRep4 bacteria with a modified inducible pQE9 expression plasmid (Qiagen) … [Read more…]