Background The stem cell factor receptor, KIT, is a target for
Background The stem cell factor receptor, KIT, is a target for the treating cancer, mastocytosis, and inflammatory diseases. (IC50) of 20040 nM (Desk 1 and Amount 1B). Kinetic research where ATP and masitinib had been covaried demonstrated that at concentrations 500 nM masitinib is normally a competitive inhibitor against ATP, but at higher concentrations ( … [Read more…]