Background Homeodomain-interacting protein kinase-2 (HIPK2) performs an essential function in restraining
Background Homeodomain-interacting protein kinase-2 (HIPK2) performs an essential function in restraining tumor progression as it might regulate, alone or within multiprotein complexes, many proteins (generally transcription elements) involved with cell development and apoptosis. by traditional western immunoblotting. Outcomes HIPK2 overexpression in tumor cells downregulated VEGF mRNA VEGF and amounts promoter activity. The VEGF downregulation was … [Read more…]