Purpose To research functional interactions between your phosphatidylinositol 3-kinase (PI3K)/Akt pathway
Purpose To research functional interactions between your phosphatidylinositol 3-kinase (PI3K)/Akt pathway as well as the nuclear aspect erythroid 2-related aspect 2 (Nrf2)-reliant antioxidant program in cultured human retinal pigment epithelium (RPE) cells. PI3K inhibitors wortmannin Vaccarin IC50 and “type”:”entrez-nucleotide”,”attrs”:”text message”:”LY294002″,”term_id”:”1257998346″,”term_text message”:”LY294002″LY294002 triggered dose-dependent mobile and mitochondrial GSH depletion and downregulation Vaccarin IC50 from the modulatory … [Read more…]