In general, domiciled animal populations or under the responsibility of owners have a lower frequency of anti-antibodies compared to stray or shelter populations [4, 18, 47, 55, 77, 79]. a concentration observed mainly in the west and north zones of Rio de Janeiro city. The results emphasize the importance of adopting prophylactic measures to control transmission in domiciled dogs and cats in Rio de Janeiro, contributing positively to public health. Keywords: Toxoplasmosis, Companion animals, Serology, Rio Amyloid b-peptide (1-40) (rat) de Janeiro metropolitan region Amyloid b-peptide (1-40) (rat) Rsum est un parasite zoonotique trs rpandu au Brsil, capable dinfecter les mammifres et les oiseaux. Laugmentation des populations urbaines danimaux de compagnie et le rtrcissement de la relation homme-animal peuvent faciliter la transmission de zoonoses importantes pour la sant publique, telles que la toxoplasmose. Cette tude visait valuer la frquence et la distribution spatiale de linfection et ses facteurs de risque chez les chiens et les chats domicilis qui ont frquent lInstitut Jorge Vaitsman de Rio de Janeiro. Des chantillons de srum de 400 chiens et 272 chats ont t valus par un test dimmunofluorescence indirecte (IFAT) pour les anticorps IgG anti-taient largement rpartis dans la rgion mtropolitaine de ltat de Rio de Janeiro, avec une concentration observe principalement dans les zones Amyloid b-peptide (1-40) (rat) ouest et nord de la ville de Rio de Janeiro. Les rsultats soulignent limportance dadopter des mesures prophylactiques pour contr?ler la transmission de chez les chiens et les chats domicilis Rio de Janeiro, contribuant positivement la sant publique. Introduction The protozoan is a globally distributed parasite capable of infecting homeothermic animals [19, 82]. Felids, including domestic cats, are definitive hosts because they are able to spread oocysts in the environment through feces, only in the days following the first infection [20, 53]. High humidity and temperatures above 30 C favor the sporulation and maintenance of the oocysts in the environment [85]. However, high temperatures above 60 C are Rabbit Polyclonal to OR10A4 able to inactivate oocysts and cysts, the major parasite structures related to transmission for their hosts [22, 28]. For humans, the main transmission routes are the ingestion of raw or undercooked meat containing tissue cysts, and contaminated raw food and water with sporulated oocysts, or transplacental transmission [27]. In the urban context, domestic cats are considered the key host in the epidemiology of infection, as they are responsible for contamination of the environment shared with humans [17, 29]. Domestic dogs, as well as other mammals, including humans, and birds, are intermediate hosts. The diet is an important factor for infection by in domestic dogs and cats [25, 29]. The supply of leftovers, homemade food, and offal for these animals, especially dogs, may indicate possible sources of infection shared with humans. In Brazil, Amyloid b-peptide (1-40) (rat) there is high genetic diversity of strains, including highly virulent clonal and atypical genotypes, isolated from different species of hosts [21, 23, 50, 59, 60, 72]. Among Brazilian people, up to 50% of elementary school children and 50C80% of women of child-bearing age have antibodies to [23]. According to Shapiro et al. [71], the high prevalence of infection in this country is related to high environmental contamination by oocysts of the parasite. In addition, toxoplasmosis can determine severe clinical manifestations in adults and children from different regions of Brazil. According to Strang et al. [78], 48% of Brazilian children with congenital toxoplasmosis can develop retinochoroiditis, and.