The resulting congenic mice developed systemic autoimmunity despite their reduced peripheral B cell numbers, in keeping with our discovering that allows autoimmunity to build up within a B lymphopenic environment
The resulting congenic mice developed systemic autoimmunity despite their reduced peripheral B cell numbers, in keeping with our discovering that allows autoimmunity to build up within a B lymphopenic environment. essential for advancement of IgG autoantibodies and renal pathology. We suggest that in A/WySnJ mice an excessive amount of BAFF per B cell rescues self-reactive … [Read more…]