Proteasomes are the main enzyme complexes for non-lysosomal proteins degradation in
Proteasomes are the main enzyme complexes for non-lysosomal proteins degradation in eukaryotic cells. precursors favouring the forming of constitutive proteasomes consequently. Here we present that proβ5 mainly promotes integration into LMP2/MECL-1-including precursors in IFNγ-activated LMP7-lacking cells and contaminated LMP7-lacking mice. This demonstrates that proβ5 will not immediate preferential integration into β1/β2-including precursors but rather promotes … [Read more…]