AMP-activated protein kinase (AMPK), a significant downstream effector from the tumor
AMP-activated protein kinase (AMPK), a significant downstream effector from the tumor suppressor liver organ kinase 1 (LKB1) and pharmacologic target of metformin, established fact to exert a precautionary and inhibitory influence on tumorigenesis; nevertheless, its part in tumor development and metastasis is not well characterized. presented by multiple hamartomatous polyps in the gastrointestinal system (Alessi … [Read more…]