Wee1 is a cell cycle-dependent kinase that’s needed for the G2-M
Wee1 is a cell cycle-dependent kinase that’s needed for the G2-M checkpoint. While hyperactivity of Wee1 kinase causes cell routine arrest in the G2-M stage, its inhibition causes early mitotic access and cell loss of life.6 Wee1 is a customer proteins of Hsp90. Moreover, Wee1 (Swe1 in fungus) kinase phosphorylates a conserved tyrosine residue in … [Read more…]