Lipopolysaccharide (LPS) in the cell envelope of Gram-negative bacterias is a
Lipopolysaccharide (LPS) in the cell envelope of Gram-negative bacterias is a primary reason behind the symptoms of sepsis. phosphorylation of Akt, ERK1/2 and PLA2 in activated platelets, and inhibitors of PI3-kinase, Akt and ERK1/2 decreased significantly LPS improved platelet function and linked ROS creation. Furthermore, inhibition of platelet cyclooxygenase or the thromboxane receptor, uncovered an … [Read more…]