Mutations in the autoimmune regulator (AIRE) gene lead to autoimmune polyendocrinopathy
Mutations in the autoimmune regulator (AIRE) gene lead to autoimmune polyendocrinopathy syndrome type 1 (APS1), characterized by the development of multi-organ autoimmune damage. #607358), has been IL3RA the focus of intense study since mutations in the gene were recognized in 1997 as the cause of autoimmune polyendocrinopathy syndrome type 1 (APS1, OMIM #2400300, also known … [Read more…]