When nerve injury occurs, the axon and myelin fragments distal to
When nerve injury occurs, the axon and myelin fragments distal to the injury site have to be cleared away before repair. issue, Gomez-Sanchez et al. now show that macroautophagy is essential for myelin breakdown and clearance in Schwann cells after nerve injury. Macroautophagy (hereafter autophagy) is usually a mass degradation pathway that delivers cytoplasmic substrates … [Read more…]