Using a polypeptide oligomer harboring 16 repeats of the neuritogenic epitope
Using a polypeptide oligomer harboring 16 repeats of the neuritogenic epitope (aa 58C73) of myelin P2 protein separated by spacers, enhancement of the immune response to the P2 protein, an important neuritogenic autoantigen in experimental autoimmune neuritis (EAN), was attempted. of Wrzburg), using solid-phase stepwise elongation on an Applied Biosystems model 430. The monomeric bovine … [Read more…]