We previously reported that upregulation of mortalin, an Hsp70 family members
We previously reported that upregulation of mortalin, an Hsp70 family members chaperone, is very important to B-RafV600E tumor cells to bypass p21CIP1 appearance, which is activated being a tumor suppressive system in response to aberrant MEK/ERK activation (Wu et al. not essential for Raf-1:ER to induce p21CIP1 transcription in LNCaP cells, where TP53 is outrageous … [Read more…]