The hypoxia-inducible transcription factors HIF-1 and HIF-2 mediate key cellular adaptions
The hypoxia-inducible transcription factors HIF-1 and HIF-2 mediate key cellular adaptions to hypoxia and donate to renal homeostasis and pathophysiology; nevertheless, little is well known about the cell typeCspecific features of HIF-1 and HIF-2 in response to ischemic kidney damage. monoclonal antibodies. On the other hand, pharmacologic or hereditary activation of HIF via HIF prolyl-hydroxylase … [Read more…]