We investigated the part of prostaglandin D2 (PGD2) signaling in acute
We investigated the part of prostaglandin D2 (PGD2) signaling in acute lung damage (ALI), concentrating on its producerCeffector relationship in vivo. for the anti-inflammatory reactions of PGD2. In vitro, DP agonism straight enhanced endothelial hurdle development, and 15-deoxy-12,14-PGJ2 attenuated both neutrophil migration and cytokine appearance. These observations reveal the fact that PGD2 signaling between alveolar … [Read more…]